Synthesis and structure of 6-bromo-2-(diethoxymethyl)- 2-hydroxy-3-phenyl-2,3-dihydro-1Himidazo[ 1,2-a]pyridin-4-ium chloride acetonitrile monosolvate

Abstract

In the title solvated molecular salt, C18H22BrN2O3+·Cl−·CH3CN, the imidazole ring is in envelope conformation and the pyridine and phenyl rings are oriented at a dihedral angle of 72.52 (5)°. In the crystal, O—H⋯Cl and N—H⋯Cl hydrogen bonds link the cations and anions into centrosymmetric tetramers enclosing R24(12) loops. Short Br⋯Cl [3.2313 (4) Å] and O⋯Cl [3.0490 (10) Å] contacts are observed. A Hirshfeld surface analysis of the structure indicates that the most important contributions for the crystal packing are from H⋯H (52.4%), H⋯C/C⋯H (12.1%), H⋯Br/Br⋯H (11.0%) and H⋯Cl/Cl⋯H (10.2%) interactions