http://hdl.handle.net/20.500.12323/4675 2026-04-04T03:27:56Z http://hdl.handle.net/20.500.12323/4684 Title: Assessment of the Diagnostic Value of IL-10 and Lactoferrin by BIRADS Categories in Breast Neoplasms Authors: Orujova, Ilaha; Asadov, Ajdar; Alakberzade, Shafiqa; Orujov, Agil Abstract: Breast cancer is the most common cancer among women around the world. The real way to improve the results of treatment of breast tumours is an early, and in some cases, preclinical diagnosis. This problem can only be solved if complex diagnostic methods are used. The aim of our work is to determine the change in the level of IL-10 and lactoferrin in the blood serum of patients with breast neoplasms corresponding to the BIRADS categories. The sensitivity, specificity, diagnostic values of these biochemical parameters and the correlation between them were also studied. According to the results of our studies, increasing levels of BIRADS would lead to a raise in the levels of IL-10 and lactoferrin in blood serum in patients with breast tumours. The results showed that lactoferrin had a high diagnostic value compared to IL-10. 2020-01-01T00:00:00Z http://hdl.handle.net/20.500.12323/4683 Title: Molecular Analysis of Glucose-6-Phosphate Dehydrogenase Gene Mutations in Azerbaijan Republic Authors: Saltanat, Aghayeva; Ayaz, Mammadov; Arndt, Rolfs; Volha, Skrahina; Elkhan, Rasulov; Elvira, Guliyeva Abstract: Genetic screening of school children in Masalli region in Azerbaijan Republic identified 23 school children with G6PD enzyme activity different deficiency (from 0 up to 60% activity). Biochemical studies were done/performed for school children with activity efficiency on enzyme preparations from erythrocytes. As to WHO Guidelines, enzymatic preparations were related to the following classes: 2nd class – 13 boys, 3rd class – 6 school boys, 4th class – 4 of them. DNA molecular analysis, isolated from blood of the index patient, was classified as the 2nd class of G6PD enzyme deficiency and has shown the substitution of Guanine nucleotide with Adenine in position 1178. As a result of the mutation in protein in the position 393, substitution of amino acids Arginine with Histidine [G6PD,1178 (G-A) Arg393His] takes place. 2020-01-01T00:00:00Z http://hdl.handle.net/20.500.12323/4682 Title: Biological Characteristics of Schmallenberg Virus - an Overview Authors: Zeynalova, Shalala; Omarov, Asaf Abstract: Schmallenberg virus disease was originally reported in Germany in 2011. The new disease was diagnosed in the UK in January 2012. Currently, little information has been collected about the pathogen of the Schmallenberg virus. The virus genetically belongs to the Bunyaviridae family (Orthobunyavirus genus and Simbu serogroup). The clinical symptoms of acute SBV infection are unspecific in sheep and goats. This study characterized the origin, emergence, transmission, spread in Europe and Azerbaijan, clinical signs, and the diagnosis of this virus. Currently, the Shmallenberg disease is known to be a serious threat to Veterinary Public Health. 2020-01-01T00:00:00Z http://hdl.handle.net/20.500.12323/4681 Title: Cytokines and Peri-Implant Disease Authors: Adli, Hawa Abstract: The aim of this review was to summarize data from studies making inquiries on levels of the cytokines in pathogenesis of peri-implant diseases. Here we reviewed the recent developments on IL-1β, IL-10, IL-17, IL-21, and IL-33. We highlighted recent advances during the last few years in this area and discussed their roles in immune regulation in patients with peri-implant disease.Our results revealed that identifying the levels of these cytokines (IL-1β, IL-10, IL-17, IL-21, and IL-33) may help to predict the diagnosis of periimplant diseases. From a safety perspective, this study emphasized the need to consider the impact of these interleukin on peri-implant diseases. 2020-01-01T00:00:00Z