Prevention Of Necrobacteriosis In Huge Horns Animals

Abstract

Necrobacteriosis is widespread among the huge horns animals in the republic. The causative agents of Fusobacterium necroforum necrobacteriosis are usually harmless microorganisms which live in the usual case, in the gastrointestinal tract of ruminant animals. It is a violation of the basic calcium metabolism in the body, which turns them into the causative agents of severe pathologies of the bone tissue, muscles and internal organs of the animal. The starting mechanism of necrobacteriosis occurs after the loss of the skin's natural impermeability. This happens during mechanical damage to the skin and nails of animals, as well as in violation of mineral and vitamin metabolism in the body. At this stage, factororamill is defined as an infectious disease, necrobacteriosis requires a non-standard approach to fight against brucellosis, tuberculosis, leukemia and a number of other diseases. At first glance, vaccinating all farm animals with quality vaccines seems to be the solution/ OR: At the first glance, the solution seems to be vaccinating all farm animals with quality vaccines. However, the perpetrators of these diseases are observed living inside the animal`s body. The animal's immune system reacts weakly to the presence of the causative agent of this disease - in the process of evolution, the pathogen is genetically close to the host's body, and in this case, the vaccine does not give/show/come with the desired effect. Only when a stressful situation arises - low-quality diet, care, delivery, transportation, etc. When the immune balance between the host organism and the pathogen is disturbed, the clinical signs of the disease manifest themselves. Therefore, the prevention of diseases from this group should be focused on prevention, elimination of stressful situations and the identification of latent carriers of the pathogen in animals. An example is the proper prevention and even complete prevention of the spread of necrobacteriosis in animals contracted/contaminated with factorial infectious disease through proper nutrition and veterinary care.During the epizootiological, clinical and pathoanatomical examinations carried out on farms, the spontaneous occurrence of these diseases in huge horned animals was studied by examining the materials taken from the nails suspected of necrobacteriosis. The pathogenicity of cultures of Fusobacterium necrophorum isolated as a result of bacteriological examination was determined on various laboratory animals, rabbits and white mice. The sensitivity of these agents to drugs was determined and their effectiveness was studied in the treatment of necrobacteriosis in laboratory experiments.